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Lovastatin and simvastatin-inhibitors of HMGCoA reductase cholesterol biosynthesisALBERTS, A. W.Cardiology. 1990, Vol 77, pp 14-21, issn 0008-6312, 8 p., SUP4Conference Paper

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. VIII, Side chain ether analogues of lovastatinLEE, T.-J; HOLTZ, W. J; SMITH, R. L et al.Journal of medicinal chemistry (Print). 1991, Vol 34, Num 8, pp 2474-2477, issn 0022-2623Article

Intestinal and hepatic cholesterogenesis in hypercholesterolemic dyslipidemia of experimental diabetes in dogsKWONG, L. K; FEINGOLD, K. R; PERIC-GOLIA, L et al.Diabetes (New York, NY). 1991, Vol 40, Num 12, pp 1630-1639, issn 0012-1797Article

Potent inhibitory effect of antibiotic 1233A on cholesterol biosynthesis which specifically blocks 3-hydroxy-3-methylglutaryl coenzyme A synthaseOMURA, S; TOMODA, H; CHABALA, J. C et al.Journal of antibiotics (Tokyo. 1968). 1987, Vol 40, Num 9, pp 1356-1357, issn 0021-8820Article

MK 287: a potent, specific, and orally active receptor antagonist of platelet-activating factorHWANG, S.-B; LAM, M.-H; SZALKOWSKI, D. M et al.Journal of lipid mediators. 1993, Vol 7, Num 2, pp 115-134, issn 0921-8319Article

3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9: The synthesis and biological evaluation of novel Simvastatin analogsHARTMAN, G. D; HALCZENKO, W; GEMERSHAUSEN, J. I et al.Journal of medicinal chemistry (Print). 1992, Vol 35, Num 21, pp 3813-3821, issn 0022-2623Article

Biochemical and pharmacological characterization of L-659,989: an extremely potent, selective and competitive receptor antagonist of platelet-activating factorSAN-BAO HWANG; MY-HANH LAM; ALBERTS, A. W et al.The Journal of pharmacology and experimental therapeutics. 1988, Vol 246, Num 2, pp 534-541, issn 0022-3565Article

Phenobarbital induces rat liver apolipoprotein A-I mRNAYU-SHENG CHAO; PICKETT, C. B; TING-ING YAMIN et al.Molecular pharmacology. 1985, Vol 27, Num 3, pp 394-398, issn 0026-895XArticle

Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat liversSINGER, I. I; KAWKA, D. W; KAZAZIS, D. M et al.Proceedings of the National Academy of Sciences of the United States of America. Biological sciences. 1984, Vol 81, Num 17, pp 5556-5560, issn 0273-1134Article

Synthesis and biological activity of the platelet-activating factor antagonist (±)-trans-2-(3-methoxy-4-phenylsulfonylethoxy-5-n-propylsulfonyl)-5-(3,4,5-trimethoxyphenyl) tetrahydrofuran (L-671,284) and its analogsBUGIANESI, R. L; PONPIPOM, M. M; PARSONS, W. H et al.Bioorganic & medicinal chemistry letters. 1992, Vol 2, Num 2, pp 181-184Article

The inhibition of cytoplasmic acetoacetyl-CoA thiolase by a triyne carbonate (L-660, 631)GREENSPAN, M. D; YUDKOVITZ, J. B; CHEN, J. S et al.Biochemical and biophysical research communications (Print). 1989, Vol 163, Num 1, pp 548-553, issn 0006-291X, 6 p.Article

Metabolism of lovastatin by rat and human liver microsomes in vitroGREENSPAN, M. D; YUDKOVITZ, J. B; ALBERTS, A. W et al.Drug metabolism and disposition. 1988, Vol 16, Num 5, pp 678-682, issn 0090-9556Article

Inhibition of hydroxymethylglutaryl-coenzyme A synthase by L-659,699GREENSPAN, M. D; YUDKOVITZ, J. B; CHABALA, J. C et al.Proceedings of the National Academy of Sciences of the United States of America. 1987, Vol 84, Num 21, pp 7488-7492, issn 0027-8424Article

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. IV: Side chain ester derivatives of mevinolinHOFFMAN, W. F; ALBERTS, A. W; ANDERSON, P. S et al.Journal of medicinal chemistry (Print). 1986, Vol 29, Num 5, pp 849-852, issn 0022-2623Article

Regulation of hepatic receptor-dependent degradation of LDL by mevinolin in rabbits with hypercholesterolemia induced by a wheat starch-casein dietCHAO, Y.-S; KROON, P. A; YAMIN, T.-T et al.Biochimica et biophysica acta. 1983, Vol 754, Num 2, pp 134-141, issn 0006-3002Article

Inhibition of 3-hydroxy-3-methylglutaryl-CoA synthase and cholesterol biosynthesis by β-lactone inhibitors and binding of these inhibitors to the enzymeGREENSPAN, M. D; BULL, H. G; YUDKOVITZ, J. B et al.Biochemical journal (London. 1984). 1993, Vol 289, pp 889-895, issn 0264-6021, 3Article

Zaragozic acids : a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthaseBERGSTROM, J. D; KURTZ, M. M; LIESCH, J. M et al.Proceedings of the National Academy of Sciences of the United States of America. 1993, Vol 90, Num 1, pp 80-84, issn 0027-8424Article

Development, synthesis, and biological evaluation of (-)-trans-(2S,5S)-2-[3-(2-oxopropyl)sulfonyl]-4-n-propoxy-5-(3-hydroxypropoxy)-phenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a potent orally active platelet-activating factor (PAF) antagonist and its water-soluble prodrug phosphate esterGIROTRA, N. N; BIFTU, T; DAVIES, P et al.Journal of medicinal chemistry (Print). 1992, Vol 35, Num 19, pp 3474-3482, issn 0022-2623Article

(±)-trans-2-(3-methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonistPONPIPOM, M. M; SAN-BAO HWANG; GRAHAM, D. W et al.Biochemical and biophysical research communications (Print). 1988, Vol 150, Num 3, pp 1213-1220, issn 0006-291X, 8 p.Article

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. III: 7-3,5-disubstituted [1,1'-biphenyl]-3,5-dihydroxy-6-heptenoic acids and their lactone derivativesSTOKKER, G. E; ALBERTS, A. W; LEE, T. J et al.Journal of medicinal chemistry (Print). 1986, Vol 29, Num 2, pp 170-181, issn 0022-2623Article

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. VII, Modification of the hexahydronaphthalene moiety of simvastatin : 5-oxygenated and 5-oxa derivativesDUGGAN, M. E; ALBERTS, A. W; SCHWARTZ, M. S et al.Journal of medicinal chemistry (Print). 1991, Vol 34, Num 8, pp 2489-2495, issn 0022-2623Article

The toxicity of a fluorinated-biphenyl HMG-CoA reductase inhibitor in beagle dogsGERSON, R. J; ALLEN, H. L; LANKAS, G. R et al.Fundamental and applied toxicology (Print). 1991, Vol 16, Num 2, pp 320-329, issn 0272-0590, 10 p.Article

On the etiology of subcapsular lenticular opacities produced in dogs receiving HMG-CoA reductase inhibitorsGERSON, R. J; MACDONALD, J. S; ALBERTS, A. W et al.Experimental eye research. 1990, Vol 50, Num 1, pp 65-78, issn 0014-4835, 14 p.Article

Plasma apolipoprotein E, high density lipoprotein 1 (HDL1) and urinary mevalonate excretion in pancreatectomized diabetic dogs : effects of insulin and lovastatinGLEESON, J. M; HEJAZI, J. S; KWONG, L et al.Atherosclerosis. 1990, Vol 84, Num 1, pp 1-12, issn 0021-9150, 12 p.Article

Toxicity of the HMG-coenzyme A reductase inhibitor, lovastatin, to rabbitsKORNBURST, D. J; MACDONALD, J. S; PETER, C. P et al.The Journal of pharmacology and experimental therapeutics. 1989, Vol 248, Num 2, pp 498-505, issn 0022-3565Article

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